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How Much Benadryl Do I Give A Dog To Put Down? [Solved]

According to this scientific paper, the lethal dose for diphenhydramine in dogs ranges between 24 to 30 mg per kilogram of body weight by IV administration. For a 40-pound dog, this would equate to about 430 to 540 mg, or 9-10 tablets (for tablets with 50mg diphenhydramine – note that some tablets are 25mg only).

How much benadryl do I give a dog to put down?

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